刘汉强

1. 基本信息

刘汉强，男，博士，1988 年 2 月生，陕西延安人。现任西北农林科技大学园艺学院讲师，硕士生导师。主要研究领域集中在黄瓜与甜瓜分子遗传学、功能基因组学与精准育种技术，包括正向遗传学定位、基因组图谱构建、基因编辑与标记辅助选择育种等。团队成果落地转化性强，兼具理论深度与实践价值。

2. 研究方向

焦于黄瓜、甜瓜等蔬菜作物的重要性状解析与分子设计育种，目标是解决产业发展中的关键科学问题，并培养具备前沿视野与实践能力的青年科研人才。主要方向包括：

（1）功能基因组与性状定位：通过多组学（基因组、转录组、代谢组）技术结合图位克隆技术，快速定位、克隆黄瓜/甜瓜抗病、果色、果形、株形等重要农艺性状调控基因；

（2）基因功能解析：利用 CRISPR/Cas9 基因编辑、超表达、RNAi 等技术，验证关键基因功能，解析蔬菜重要农艺性状形成的分子机理；

（3）种质创新与育种应用：收集优异黄瓜 / 甜瓜种质资源，创制突变体材料，将基因定位成果转化为分子标记，建立高效分子标记辅助选择育种体系，培育优质、抗逆的瓜类新品种；

3. 教育经历

2012.09-2018.12硕博连读，西北农林科技大学, 园艺学院蔬菜学, 获农学博士学位（导师：程智慧）

2016.09-2018.10博士联合培养，美国威斯康辛大学麦迪逊分校（导师：Yiqun Weng 教授）

2008.08-2012.07 本科，西北农林科技大学，园艺学院，蔬菜学，获农学学士学位。

4. 工作经历

2022.01-至今 讲师，西北农林科技大学园艺学院蔬菜学；

2018.10-2021.09 博士后，美国威斯康辛大学麦迪逊分校，园艺学院，导师: Yiqun Weng教授。

5. 科研项目

（1）陕西省重点研发项目（一般项目），2025-2026，12万元，主持；

（2）国家重点研发计划子课题（国际合作项目），2024-2026，15 万元，在研，主持；

（3）国家重点研发计划子课题，2023-2026，20 万元，在研，主持；

（4）国家自然科学基金青年项目，2023-2025，30万元，主持；

（5）西北农林科技大学科研启动项目，2022-2025，20万元，主持；

（6）黄瓜CsMKP1调控侧枝数量的分子机制研究，国家自然基金面上项目，2023-2025，54万元，参与；

（7）“黄瓜杂种优势利已结题用技术与强优势杂交种创制”，国家重点研发计划子课题，111.3万元，已结题，参与；

（8）“黄瓜嫩果白色果皮基因（w）的图位克隆和功能分析”，国家自然科学基金面上项目，82万元，已结题，参与；

（9）“营养液和光环境调控黄瓜生长发育和品质的效果及机理”，国家“863”课题子课题，33万元，已结题，参与。

6. 学术成果

[1] Hanqiang Liu, Mingming Cui, Kaihong Hu, Junyi Tan, Yiqun Weng, Yuxuan Ma, Ju Li, Zeqiang Huang, Birong Chen, Huanwen Meng, Yupeng Pan, Zhihui Cheng (2025) CsAPRR2 regulates cucumber immature fruit color by coordinating chloroplast biogenesis and photosynthesis-related gene expression. The Plant Journal.123:6

[2] Liu Hanqiang, Huang Zeqiang, Wang Xinyue, Hu Kaihong, Jiang Qinqin, Chen Feifan, Ma Yuxuan, Cheng Zhihui, Pan Yupeng, Weng Yiqun (2025) Regreening mechanisms in cucumber: insights from a CsSIG2 mutation affecting chloroplast development. Theoretical and Applied Genetics 138:82

[3] Liu Hanqiang, Hu Kaihong, Ma Yuxuan, Fu Liting, Huang Zeqiang, Cheng Zhihui, Sheng Yuyan, Li Dandan, Pan Yupeng (2025) Identification and Functional Analysis of an LTR Retrotransposon Insertion in CsPHYB Associated with Early Senescence in Cucumber (Cucumis sativus L.). Plant Science:112519

[4] Hu Kaihong, Lin Yu, Linghu Shaofeng, Zhang Fan, Sheng Yunyan, Li Dandan*, Liu Hanqiang* (2025) Genetic analysis and candidate gene mining of flowering time in cucumber under low-light stress. Vegetable Research 5

[5] Si Jia, Zhou Xiaoqing, Chen Xinyu, Ming Huilin, Liu Hanqiang, Hui Maixia (2025) Identification and characterization of a key gene controlling purple leaf coloration in non-heading Chinese cabbage (Brassica rapa). Planta 261:80

[6] Ali Muhammad, Pan Yupeng, Liu Hanqiang, Cheng Zhihui (2024) Photoperiod and temperature as dominant environmental drivers triggering chemical compositions of garlic bulb during growth. Plant Physiology and Biochemistry 216:109143

[7] Wang Xiao, Pan Yupeng, Liu Hanqiang, Meng Huanwen, Cheng Zhihui (2024) Physiological responses of cucumber seedlings to combined high-temperature and high-humidity stress at different leaf stages. Horticulturae 10:1369

[8] Yang Yuqing, Zhang Ning, Zhou Yuqing, Cui Haibing, Zhou Yuan, Zhang Huijun, Liu Hanqiang*, Pan Yupeng* (2025) BSA-Seq-based genetic mapping of fruit length regulating locus in oriental melon XNM125 and XNM020. Euphytica 221:125

[9] Yuqing Yang, Yuan Zhou, Yachen Xiang, Yuqing Zhou, Haibing Cui, Hanqiang Liu*, Yupeng Pan* (2024) Development and application of a dCAPS marker for the white immature fruit rind colour gene w in cucumber (Cucumis sativus L.). Plant Breeding

[10] Xiaoqing Zhou, Jia Si, XinYu Chen, Yongkuan Li, Hanqiang Liu*, Maixia Hui* (2024) Genetic mapping reveals a candidate gene (BraBAN) contributing to the purple leaves in non-heading Chinese cabbage. Scientia Horticulturae 338:113447

[11] Yuqing Zhou, Yuqing Yang, Yachen Xiang, Haibing Cui, Yuan Zhou, Hanqiang Liu*, Huijun Zhang*, Yupeng Pan* (2024) Bulked segregant analysis by sequencing-based genetic mapping of the green spotted fruit rind regulating locus in wild melon XNM020 reveals four possible candidate genes. Agronomy 14:1106

[12] Hanqiang Liu, Jianyu Zhao, Feifan Chen, Zhiming Wu, Junyi Tan, Nguyen NH, Zhihui Cheng, Yiqun Weng (2023) Improving Agrobacterium tumefaciens−Mediated Genetic Transformation for Gene Function Studies and Mutagenesis in Cucumber (Cucumis sativus L.). Genes 14:601

[13] Lijun Qiao, Yuqing Yang, Yuqing Zhou, Haibing Cui, Yuan Zhou, Chunqiu Liu, Yunzhao Zhou, Hanqiang Liu*, Zhihui Cheng*, Yupeng Pan* (2023) Fine genetic mapping of the Mottled Rind Color (Morc) locus reveals a 4895-bp presence-absence variation contributing to the mottled or unmottled fruit rind color in cucumber. Scientia Horticulturae 321:112303

[14] Hanqiang Liu, Yiqun Weng (2022) Agrobacterium tumefaciens-mediated genetic transformation in cucumber. The Cucumber Genome. Springer, pp 55-69

[15] Li Ningyang, Zhang Xueyu, Sun Xiudong, Zhu Siyuan, Cheng Yi, Liu Meng, ...Liu Hanqiang, ...et al. Genomic insights into the evolutionary history and diversification of bulb traits in garlic. Genome Biology 2022;23:188

[16] Luming Yang, Hanqiang Liu, Jianyu Zhao, Yupeng Pan, Siyuan Cheng, Calvin D Lietzow, Changlong Wen, Xiaolan Zhang, Yiqun Weng. LITTLELEAF (LL) encodes a WD40 repeat domain‐containing protein associated with organ size variation in cucumber. The Plant Journal 2018, 95:834-847

[17] Zhang Chaowen, Chen Feifan, Zhao Ziyao, Hu Liangliang, Liu Hanqiang, Cheng Zhihui, Weng Yiqun, Chen Peng, Li Yuhong (2018) Mutations in CsPID encoding a Ser/Thr protein kinase are responsible for round leaf shape in cucumber (Cucumis sativus L.). Theoretical and Applied Genetics 131:1379-1389

[18] Hanqiang Liu, Jianqing Jiao, Xinjing Liang, Jia Liu, Huanwen Meng, Shuxia Chen, Yuhong Li, Zhihui Cheng. Map-based cloning, identification and characterization of the w gene controlling white immature fruit color in cucumber (Cucumis sativus L.). Theoretical and Applied Genetics, 2016, 129:1247-1256

[19] Hanqiang Liu, Huanwen Meng, Yupeng Pan, Xinjing Liang, Jianqing Jiao, Yuhong Li, Shuxia Chen, Zhihui Cheng. Fine genetic mapping of the white immature fruit color gene w to a 33.0-kb region in cucumber (Cucumis sativus L.). Theoretical and Applied Genetics, 2015, 128:2375-2385

[20] Jianqing Jiao, Hanqiang Liu, Jia Liu, Mingming Cui, Jing Xu, Huanwen Meng, Yuhong Li, Shuxia Chen, Zhihui Cheng. Identification and functional characterization of APRR2 controlling green immature fruit color in cucumber (Cucumis sativus L.). Plant Growth Regulation, 2017, 83:233-243

[21] Yupeng Pan, Xinjing Liang, Meiling Gao, Hanqiang Liu, Huanwen Meng, Yiqun Weng, Zhihui Cheng. Round fruit shape in WI7239 cucumber is controlled by two interacting quantitative trait loci with one putatively encoding a tomato SUN homolog. Theoretical and applied genetics, 2017, 130:573-586

[22] Chaowen Zhang, Feifan Chen, Ziyao Zhao, Liangliang Hu, Hanqiang Liu, Zhihui Cheng, Yiqun Weng, Peng Chen, Yuhong Li. Mutations in CsPID encoding a Ser/Thr protein kinase are responsible for round leaf shape in cucumber (Cucumis sativus L.). Theoretical and Applied Genetics, 2018, 131:1379-1389

[23] Yinxin Dong, Zhihui Cheng, Huanwen Meng, Hanqiang Liu, Cuinan Wu, Abdul Rehman Khan. The effect of cultivar, sowing date and transplant location in the field on bolting of welsh onion (Allium fistulosum L.). BMC plant biology, 2013, 13:1-12

[24] 张会梅, 杜军志, 许忠民, 刘汉强 (2024) 薄皮甜瓜新品种“蜜脆9号”的选育.北方园艺:157-160

[25] 仝培江, 孟焕文, 潘玉朋, 刘汉强, 程智慧 (2023) 高温和高湿环境对不同生态型黄瓜幼苗生长的影响. 中国蔬菜:85-91

[26] 刘汉强. 黄瓜高效遗传转化体系的建立和嫩果白皮基因w的图位克隆与功能分析 [博士学位论文]. 西北农林科技大学, 杨凌, 2018

7. 通讯方式

电话：19891417052

办公室：园艺学院620室

Email: hanqiang0216@nwafu.edu.cn 或 hanqiang0216@163.com

通讯地址：陕西咸阳市杨凌区李台街道邰城路3号西北农林科技大学（南校区）；邮编：712100。